HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Amino-1-cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid → HCID 15288434, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Amino-1-cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | HCID 13910947 | — |
| Reactant | N-methyl-3-(3-pyrrolidinyl)benzenemethanamine | HCID 15288432 | — |
| Product | HCID 15288434 | HCID 15288434 | 55% |
Reaction Steps
Starting from 5-amino-1-cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid (0.52 g, 1.7 mmol) and N-methyl-3-(3-pyrrolidinyl)benzenemethanamine, a procedure analogous to that given in Example 1 provided the title compound (0.44 g, 55%) as a yellow solid, mp >270° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05446044 |
| Source dataset | uspto-grants-1995_08 |
| ORD ID | ord-b1aa8ba4787042ee8d78864fd94f5446 |
| Source note | uspto-grants-1995_08 |