Benzyl Bromide → 3-Benzyloxy-4-(1-adamantyl)benzoic acid

Participants

Reaction Steps

18 g (63 mM) of the ester obtained in Example 9(a) are treated with benzyl bromide under the conditions described in Example 5(a) to lead, after the same treatment, to 17.5 g (74%) of methyl 3-benzyloxy-4-(1-adamantyl)benzoate. The derivative obtained is then saponified under the conditions described in Example 7(b) to lead, after the same treatment, to 13.6 g (96.6%) of the expected derivative, of melting point 240° C.

Provenance & Evidence