HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloride → 4-Benzyloxy-2-amino-N-[3-benzyloxy-4-(1-adamantyl)benzoyl]aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloride | HCID 312 | — |
| Reactant | 4-(Benzyloxy)benzene-1,2-diamine | HCID 13162239 | — |
| Reactant | 3-Benzyloxy-4-(1-adamantyl)benzoic acid | HCID 17867034 | — |
| Solvent | Ethyl acetate hexane | HCID 21226206 | — |
| Product | 4-Benzyloxy-2-amino-N-[3-benzyloxy-4-(1-adamantyl)benzoyl]aniline | HCID 19387997 | — |
Reaction Steps
2.7 g (12.7 mM) of 2-amino-4-(benzyloxy)aniline and 5 g (12.7 mM) of the chloride of 3-benzyloxy-4-(1-adamantyl)benzoic acid are treated under the conditions described in Example 1(f) to lead, after the same treatment andchromatography on silica in the ethyl acetate/hexane (30/70) eluent, to 4.2g (59.3%) of the expected derivative, of melting point 178° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05446059 |
| Source dataset | uspto-grants-1995_08 |
| ORD ID | ord-80dc34528c724dc8bde4c17d3c45284a |
| Source note | uspto-grants-1995_08 |