HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → (4-Bromobenzylidene)(1-isopropyl-2-methylpropyl)amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 4-Bromobenzaldehyde | HCID 70741 | — |
| Reactant | 3-Pentanamine, 2,4-dimethyl- | HCID 77702 | — |
| Catalyst | p-Toluenesulfonic acid | HCID 6101 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | (4-Bromobenzylidene)(1-isopropyl-2-methylpropyl)amine | HCID 15225580 | 94.9% |
Reaction Steps
A mixture of 4-bromobenzaldehyde (7.3 g, 40.0 mmol), 2,4-dimethylpent-3-ylamine (4.8 g, 41.4 mmol), and para-toluenesulfonic acid (0.05 g, 0.29 mmol) in 125 mL of toluene was heated under reflux while water was removed with a Dean-Stark trap. The toluene then was removed under vacuum and distillation of the remaining residue gave (4-bromobenzylidene) (1-isopropyl-2-methylpropyl)amine (10.71 g) as a clear colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05446121 |
| Source dataset | uspto-grants-1995_08 |
| ORD ID | ord-974f63f3a8a5470b8377be34e75da6fc |
| Source note | uspto-grants-1995_08 |