Formaldehyde → HCID 19388427, compound

Participants

Reaction Steps

In 10 ml of ethanol was dissolved 0.86 g of 35% formaline. To the solution was dropwise added under chilling with ice a solution of 2.35 g of methyl 1-piperazinecarbodithioate in 4 ml of ethanol. The resulting mixture was then stirred for 30 min. at room temperature. Under chilling with ice, a solution of 1.54 g of 2,6-dimethoxyphenol in 4 ml of ethanol was to the stirred mixture. The resulting mixture was stirred for one hour at room temperature, and then refluxed under heating for 38 hours. The refluxed mixture was then cooled to room temperature. Precipitated crystals were collected by filtration and then washed with ethanol to give 1.94 g of thedesired compound a whilte crystalline product, yield 56.7%.

Provenance & Evidence