Carbon Disulfide → HCID 19388433, compound

HRID 1757542Notes

Reaction equation

HRID 1757542 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([N:13]2[CH2:18][CH2:17][NH:16][CH2:15][CH2:14]2)[CH:6]=[C:7]([O:11][CH3:12])[C:8]=1[O:9][CH3:10].[C:19](=[S:21])=[S:20]>CO>[CH3:12][O:11][C:7]1[CH:6]=[C:5]([N:13]2[CH2:18][CH2:17][N:16]([C:19]([SH:21])=[S:20])[CH2:15][CH2:14]2)[CH:4]=[C:3]([O:2][CH3:1])[C:8]=1[O:9][CH3:10]

Participants

4

Reactant 2

HCID 6348Carbon DisulfideHCID 38387651-(3,4,5-Trimethoxyphenyl)piperazine

Product 1

HCID 19388433HCID 19388433, compoundYield 77.7%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In a nitrogen atmosphere, 1.9 g of 1-(3,4,5-trimethoxyphenyl)piperazine wasdissolved in 10 ml of methanol. To the solution was dropwise added under chilling with ice 0.46 ml of carbon disulfide. After the addition was complete, the mixture was stirred at room temperature for 2 hours. Precipitated crystals were collected by filtration to give 1.9 g of the desired compound as a gray-brown powder, m.p. 183°-190° C. (decomp.), yield 77.7%.

Workup

  1. additionTo the solution was dropwise added
  2. additionAfter the addition
  3. customPrecipitated crystals
  4. filtrationwere collected by filtration

Sources & evidence

ORD record
ord-e68714948013494c86c8a901112ba0fa
Source dataset
uspto-grants-1995_08
Patent number
US05446146

Reaction notes

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