Methyl iodide → HCID 19388494, compound

Participants

Reaction Steps

In 25 ml of methanol was dissolved 5.00 g (19.8 mmol.) of 1-benzhydrylpiperazine. To the solution was dropwise added under chilling with ice a solutin of 1.51 g (19.8 mmol.) of carbon disulfide in 5 ml of methanol. The mixture was then stirred for 30 min. Under chilling with ice, to the stirred mixture was added a solution of 3.80 g (19.8 mmol.) of28%-sodium methylate-in-methanol solution. The mixture was then stirred until the mixture gave a clear solution. To this was added a solution of 2.90 g (19.8 mmol.) of 97%-iodomethane in 5 ml of methanol. The mixture was then stirred at room temperature for 1.5 hours. Precipitated crystals were collected by filtration and washed with methanol, to give 5.78 g of methyl 4-diphenylmethyl-1-piperazinecarbodithioate.

Provenance & Evidence