HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → HCID 9806308, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | HCID 10904659 | HCID 10904659 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 9806308 | HCID 9806308 | 37% |
Reaction Steps
A mixture of 6-[(3-fluoro-5-[4-methoxy-3,4,5,6-tetrahydro-2H-pyran-4-yl]phenoxy)methyl]quinoline (0.367 g), methyl iodide (0.13 ml), toluene (1 ml) and acetonitrile (6 ml) was stirred at ambient temperature for 16 hours. The precipitate was filtered off to give 6-[(3-fluoro-5-[4-methoxy-3,4,5,6-tetrahydro-2H-pyran-4-yl]phenoxy)methyl]-1-methylquinolinium iodide (0.19 g) in 37% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05446165 |
| Source dataset | uspto-grants-1995_08 |
| ORD ID | ord-8065094afb984a8a8afa09b5a66a6395 |
| Source note | uspto-grants-1995_08 |