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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1757649Generated: October 25, 2026

3',4',5'-Trimethoxyacetophenone → 3-(4-Hydroxy-3-methoxy-5-nitrophenyl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one

https://huagongshe.com/reaction/1757649

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3',4',5'-TrimethoxyacetophenoneHCID 14345—
Reactant5-NitrovanillinHCID 81134—
Product3-(4-Hydroxy-3-methoxy-5-nitrophenyl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-oneHCID 3430178—

Reaction Steps

The procedure described in Example 8 was repeated by using 2.0 g of 4-hydroxy-3-methoxy-5-nitrobenzaldehyde and 2.1 g of 3',4',5'-trimethoxyacetophenone. Yield 2.2 g (57%), m.p. 123°-125° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05446194
Source datasetuspto-grants-1995_08
ORD IDord-89f5102d821c4ed98e09f1fb2a737e5c
Source noteuspto-grants-1995_08