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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1757661Generated: November 3, 2026

Acetophenone → 1-Phenyl-3-(3,4-dihydroxy-5-trifluoromethylphenyl)prop-2-en-1-one

https://huagongshe.com/reaction/1757661

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetophenoneHCID 7410—
Reactant3,4-Dihydroxy-5-(trifluoromethyl)benzaldehydeHCID 19389188—
Product1-Phenyl-3-(3,4-dihydroxy-5-trifluoromethylphenyl)prop-2-en-1-oneHCID 54013959—

Reaction Steps

The procedure described in Example 8 was repeated using 2.06 g of 3,4-dihydroxy-5-trifluoromethylbenzaldehyde and 1.20 g of acetophenone. Yield 2.19 g (71%), m.p. 196°-210° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05446194
Source datasetuspto-grants-1995_08
ORD IDord-013d97f10a2b42ddb08318a9b8cf32fb
Source noteuspto-grants-1995_08