HCID 19389110, compound → HCID 19389136, compound

Participants

Reaction Steps

A mixture of 0.918 g of N-(carboxymethyl)-N-[3-(octadecyloxy)-5-[5-[2,3-bis(phenylmethoxy)phenyl]pentoxy]phenyl]glycine and 0.3 g of 10% palladium on carbon in 50 ml of tetrahydrofuran was stirred under a hydrogen atmosphere for 4 hours when absorption ceased. The catalyst was removed by filtration through a Celitepad and the filtrate was concentrated to a solid which was triturated with hexane and filtered to give 0.653 g (92% yield, mp 129°-131°) of N-(carboxymethyl)-N-[3-[5-(2,3-dihydroxyphenyl)pentoxy]-5-(octadecyloxy)phenyl]glycine.

Provenance & Evidence