Trifluoroacetic acid → HCID 19388970, compound

Participants

Reaction Steps

A solution of 2.65 g (5.2 mmol) of 3-(methylthio)-5-(octadecyloxy)phenylcarbamic acid dimethylethyl ester and2.0 ml (26 mmol) of trifluoroacetic acid in 50 ml of methylene chloride waskept at room temperature for 24 hours. The mixture was concentrated at reduced pressure and the residue was treated with excess NaHCO3 solution. The product was extracted with methylene chloride and the dried extract was concentrated and recrystallized from methylene chloride-hexaneto give 1.85 g (87% yield), nap 75°-77° of 3-(methylthio)-5-(octadecyloxy)benzenamine. The nmr and mass spectra were consistent with the structure.

Provenance & Evidence