HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → 4-Chloro-2-isopropylamino-6-methylamino-5-pyrimidinecarbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | Isopropylamine | HCID 6363 | — |
| Reactant | 4,6-Dichloro-2-ethylamino-5-pyrimidinecarbonitrile | HCID 20510256 | — |
| Product | 4-Chloro-2-isopropylamino-6-methylamino-5-pyrimidinecarbonitrile | HCID 20510201 | — |
Reaction Steps
This compound was prepared in the manner of Example XVII, substituting 4,6-dichloro-2-isopropylamino-5-pyrimidinecarbonitrile and aqueous 40% methylamine for 4,6-dichloro-2-ethylamino-5-pyrimidinecarbonitrile and isopropylamine. The reaction product was recrystallized from methylcyclohexane to give 4-chloro-2-isopropylamino-6-methylamino-5-pyrimidinecarbonitrile; mp, 170°-173°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | USRE031136 |
| Source dataset | uspto-grants-1983_02 |
| ORD ID | ord-080deb22fe034a78876c7d4f7879f312 |
| Source note | uspto-grants-1983_02 |