HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → 4-(Bromomethyl)-2-fluoro-1,1′-biphenyl
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 2-FLUORO-4-METHYLBIPHENYL | HCID 10899366 | — |
| Product | 4-(Bromomethyl)-2-fluoro-1,1′-biphenyl | HCID 13020229 | — |
Reaction Steps
In this instance the 2-fluoro-4-methylbiphenyl was heated to 140° to 170° C. with a heating mantle and under irradiation with light without a solvent while one equivalent of Br2 was added dropwise. Subsequent NMR analysis showed the starting material:monobromide:dibromide ratio to be 25:58:18.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04371473 |
| Source dataset | uspto-grants-1983_02 |
| ORD ID | ord-5acf6064de43464c834759a5698dc925 |
| Source note | uspto-grants-1983_02 |