Phenyl isocyanate → HCID 12876118, compound

HRID 1757953Notes

Reaction equation

HRID 1757953 reaction equation
[CH2:1]([N:3]([CH3:7])[C:4]([NH2:6])=[O:5])[CH3:2].[C:8]1([N:14]=[C:15]=[O:16])[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>O1CCOCC1>[CH2:1]([N:3]([CH3:7])[C:4]([NH:6][C:15]([NH:14][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)=[O:16])=[O:5])[CH3:2]

Participants

4

Reactant 2

HCID 7672Phenyl isocyanateHCID 3032104HCID 3032104, compound

Product 1

HCID 12876118HCID 12876118, compoundYield 65.1%

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

In 50 ml of anhydrous dioxane, 7.7 g (0.075 mole) of 1-ethyl-1-methyl-urea was dissolved, into this solution 8.9 g (0.075 mole) of phenylisocyanate was added dropwise under stirring condition. The reaction was continued at a room temperature for 15 hours, then the precipitate thus formed was obtained by filtration and recrystallized from ethanol to obtain 10.8 g (yield 65%) of 1-ethyl-1-methyl-5-phenylbiuret having a melting point of 157°-159° C.

Workup

  1. additionwas added dropwise
  2. customthe precipitate thus formed
  3. customwas obtained by filtration
  4. customrecrystallized from ethanol

Sources & evidence

ORD record
ord-3b0b7ff400fd48408ecc41736322347f
Source dataset
uspto-grants-1983_02
Patent number
US04371544

Reaction notes

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