Sodium Carbonate → HCID 57010139, compound

HRID 1758043Notes

Reaction equation

HRID 1758043 reaction equation
[O:1]=[C:2]1[S:6][C:5]([C:7](=[N:13][O:14][CH3:15])[C:8]([O:10]CC)=[O:9])=[CH:4][S:3]1.C(=O)([O-])[O-].[Na+].[Na+]>C(O)C.O>[O:1]=[C:2]1[S:6][C:5]([C:7](=[N:13][O:14][CH3:15])[C:8]([OH:10])=[O:9])=[CH:4][S:3]1

Participants

5

Reactant 2

HCID 10340Sodium CarbonateHCID 57158746HCID 57158746, compound

Product 1

HCID 57010139HCID 57010139, compoundYield 49.8%

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 962WaterSolvent

Procedure

To a solution of thus obtained ethyl 2-(2-oxo-1,3-dithiol-4-yl)-2-methoxyiminoacetate (anti isomer, 1.7 g.) in ethanol (20 ml.) was added dropwise a solution of sodium carbonate 10 hydrate (2.2 g.) in water (10 ml.) and the mixture was stirred at room temperature for 3 hours. After removing ethanol from the resultant solution in vacuo, the residue was acidified with hydrochloric acid and extracted with diethyl ether. The extract was washed with a saturated aqueous solution of sodium chloride, dried over magnesium sulfate, and concentrated in vacuo to give oily product The oil was allowed to stand in a refrigerator to give 2-(2-oxo-1,3-dithiol-4-yl)-2-methoxyiminoacetic acid (anti isomer, 0.75 g.).

Workup

  1. customAfter removing ethanol from the resultant solution in vacuo
  2. extractionextracted with diethyl ether
  3. washThe extract was washed with a saturated aqueous solution of sodium chloride
  4. dry with materialdried over magnesium sulfate
  5. concentrationconcentrated in vacuo
  6. customto give oily product The oil

Sources & evidence

ORD record
ord-edf95813d1d04274a5ae4ae85cc47b4e
Source dataset
uspto-grants-1983_02
Patent number
US04371531

Reaction notes

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