Catechol → 4-Chlorocatechol

HRID 1758135Notes

Reaction equation

[C:1]1([C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4])[OH:2].ClCl.S(Cl)([Cl:14])(=O)=O>>[Cl:14][C:6]1[CH:5]=[C:3]([OH:4])[C:1](=[CH:8][CH:7]=1)[OH:2]

Participants

Reactant 3

HCID 289Catechol

HCID 24526Chlorine

HCID 24648Sulfuryl chloride

Product 1

HCID 164964-Chlorocatechol

Procedure

For example, chlorination of catechol with either chlorine or sulfuryl chloride, Berichte 44, 2182 (1911), C.A. 5, 3433 (1911) gives 4-chlorocatechol as the major product, whereas excess halogen yields the 4,5-dichlorocatechol. ##STR14##

Sources & evidence

ORD record: ord-e3e454a3f1524565b12d16b16096241e
Source dataset: uspto-grants-1983_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04371736

Reaction notes

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