Potassium Carbonate → HCID 20510875, compound

Participants

Reaction Steps

To a mixture of 3.0 grams (0.023 mole) of 2-mercaptophenol and 7.0 grams of potassium carbonate stirring in 50 ml of dimethylformamide, 4.0 grams of 2,5-dichloropyridine is added and the mixture stirred overnight at room temperature. After stirring overnight, 4.0 grams of 2-chloro-5-nitropyridine is added and the mixture is again stirred at room temperature overnight. Excess H2O is then added to the reaction mixture and the aqueous mixture extracted with ethyl ether (200 ml), washed with saturated NaHCO3, H2O, brine, dried (MgSO4), filtered, and evaporated to yield the crude product.

Provenance & Evidence