反应详情

A mixture of 96.7 mmole of 5-methyl-4-(2-propenyl)-2-phenylsulfenylcyclohexanone and 10 g. (100 mmole) of calcium carbonate in 300 ml. of toluene was heated at 110° C. for 40 minutes. The reaction was cooled, magnesium sulfate added and filtered. The filtrate was evaporated and the residue purified via column chromatography on 300 g. of silica gel eluted with 20% ether-hexane and then distillation to yield 7.61 g. (52%) of the title compound.

1. temperatureThe reaction was cooled
2. filtrationfiltered
3. customThe filtrate was evaporated
4. customthe residue purified via column chromatography on 300 g
5. washof silica gel eluted with 20% ether-hexane
6. distillationdistillation
7. customto yield 7.61 g