Ethylene Glycol → HCID 20510569, compound

Participants

Reaction Steps

To a mixed solvent consisting of 1.0 g of ethylene glycol and 1.0 g of t-butanol were added 3.9 g of 3-(2-lauroyloxyethyl)-7,7,9,9-tetramethyl-1,3,8-triazaspiro[4.5]decane-2,4-dione and 1.2 g of 2,2-bis[p-(2,3-epoxypropoxy)phenyl]propane; the mixture was heated at 110°-120° C. for 60 hours and then at 160° C. for an additional 1 hour. After completion of the reaction, benzene was added to the reaction mixture, and the benzene solution was washed with water and condensed by evaporation under reduced pressure. The residue was washed with n-hexane and the resulting solid mass was purified by column chromatography using silica gel eluted with a 20:20:1 by volume mixture of benzene, ethyl acetate and methanol. The desired Compound No. 294 was obtained in the form of a white powder and had an Rf value of 0.64 on thin-layer chromatography on silica gel developed with a 10:10:1 by volume mixture of benzene, ethyl acetate and methanol.

Provenance & Evidence