4-Hydroxy-2,2,6,6-tetramethylpiperidine → Bis[2-hydroxy-3-(4-hydroxy-2,2,6,6-tetramethylpiperidino)propyl]adipate

HRID 1758207Notes

Reaction equation

HRID 1758207 reaction equation
[OH:1][CH:2]1[CH2:7][C:6]([CH3:9])([CH3:8])[NH:5][C:4]([CH3:11])([CH3:10])[CH2:3]1.[C:12]([O:25][CH2:26][CH:27]1[O:29][CH2:28]1)(=[O:24])[CH2:13][CH2:14][CH2:15][CH2:16][C:17]([O:19][CH2:20][CH:21]1[O:23][CH2:22]1)=[O:18]>>[OH:23][CH:21]([CH2:22][N:5]1[C:6]([CH3:8])([CH3:9])[CH2:7][CH:2]([OH:1])[CH2:3][C:4]1([CH3:11])[CH3:10])[CH2:20][O:19][C:17](=[O:18])[CH2:16][CH2:15][CH2:14][CH2:13][C:12]([O:25][CH2:26][CH:27]([OH:29])[CH2:28][N:5]1[C:4]([CH3:11])([CH3:10])[CH2:3][CH:2]([OH:1])[CH2:7][C:6]1([CH3:9])[CH3:8])=[O:24]

Participants

3

Reactant 2

HCID 754714-Hydroxy-2,2,6,6-tetramethylpiperidineHCID 759871,6-Bis(2-oxiranylmethyl) hexanedioate

Product 1

HCID 70531574Bis[2-hydroxy-3-(4-hydroxy-2,2,6,6-tetramethylpiperidino)propyl]adipate

Procedure

A mixture of 18.0 g of 4-hydroxy-2,2,6,6-tetramethylpiperidine and 11.3 g of bis(2,3-epoxypropyl) adipate was reacted and treated following substantially the same procedure as described in Example 45. The desired Compound No. 122 was obtained in the form of a pale yellow, very viscous product having an Rf value of 0.33 on thin-layer chromatography on silica gel developed with a 20:4:2:1 by volume mixture of ethyl acetate, benzene, ethanol and triethylamine.

Workup

  1. customwas reacted
  2. additiontreated

Sources & evidence

ORD record
ord-f32392643e7b40c6a9f485adb0279487
Source dataset
uspto-grants-1983_02
Patent number
US04371644

Reaction notes

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