HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Cyanide → Ethyl N-(alpha-Cyanobenzyl)-1-Aminocyclopropane Carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Cyanide | HCID 768 | — |
| Reactant | Ethyl 1-[(E)-benzylideneamino]cyclopropane-1-carboxylate | HCID 12783664 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Ethyl N-(alpha-Cyanobenzyl)-1-Aminocyclopropane Carboxylate | HCID 20509670 | 100% |
Reaction Steps
Liquid HCN (2.4 ml; 0.062 M) was added to a solution of ethyl N-benzylidene-1-aminocyclopropane carboxylate (5.61 g, obtained as described in Example 1) in ethanol (25 ml) at room temperature. The solution was stirred at room temperature for forty eight hours; subsequently the excess ethanol was evaporated. The desired product was obtained in a yield of 100% (6.3 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04372776 |
| Source dataset | uspto-grants-1983_02 |
| ORD ID | ord-4e8c6a4c35d94407b130d7dcda03c120 |
| Source note | uspto-grants-1983_02 |