反应详情

The above reaction product obtained in step (a) is mixed with 600 ml of benzene and 60 ml of thionyl chloride, and left to stand for 18 hours at room temperature. The reaction solution is concentrated and subsequently partitioned between benzene and ice-water. After the organic phase is washed, dried and evaporated, the heading compound remains as an orange, semi-crystalline crude product, which is used in step (c) without further purification.

1. waitleft
2. concentrationThe reaction solution is concentrated
3. customsubsequently partitioned between benzene and ice-water
4. washAfter the organic phase is washed
5. customdried
6. customevaporated
7. customis used in step (c) without further purification