Thiophenol → HCID 178420567, compound

Participants

Reaction Steps

Mercaptobenzene (1.3 g) and 5-(3-bromopropyl)thio-1,2,3,4-tetrazole (1.8 g) are dissolved in acetone (50 ml), and thereto is added potassium carbonate (1.4 g), and the mixture is refluxed for 2 hours. After acetone is distilled off, water is added to the residue, and the mixture is extracted with chloroform. The chloroform layer is washed with 5% aqueous sodium hydroxide and saturated aqueous sodium chloride and dried over magnesium sulfate. After chloroform is distilled off, the residue is purified by column chromatography (Wakogel C-200, eluting agent, chloroform) to give 5-(3-phenylthiopropyl)thio-1,2,3,4-tetrazole (1.5 g) as colorless liquid.

Provenance & Evidence