O-((2-methylthiazol-4-yl)methyl)hydroxylamine → HCID 53718792, 화합물

HRID 1758387노트

반응식

HRID 1758387 반응식
[CH:1]([NH:3][C:4]1[S:5][CH:6]=[C:7]([C:9](=O)[C:10]([OH:12])=[O:11])[N:8]=1)=[O:2].[CH3:14][C:15]1[S:16][CH:17]=[C:18]([CH2:20][O:21][NH2:22])[N:19]=1>CO>[CH:1]([NH:3][C:4]1[S:5][CH:6]=[C:7]([C:9](=[N:22][O:21][CH2:20][C:18]2[N:19]=[C:15]([CH3:14])[S:16][CH:17]=2)[C:10]([OH:12])=[O:11])[N:8]=1)=[O:2]

참가 물질

4

반응물 2

HCID 425143O-((2-methylthiazol-4-yl)methyl)hydroxylamineHCID 13116693(2-Formamido-1,3-thiazol-4-yl)(oxo)acetic acid

생성물 1

HCID 53718792HCID 53718792, 화합물수율 65.2%

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

A mixture of 2-(2-formamidothiazol-4-yl)glyoxylic acid (1.10 g.) and 2-methylthiazol-4-ylmethoxyamine (0.99 g.) in methanol (17 ml.) was stirred at room temperature for 3 hours. The precipitates were collected by filtration and washed with methanol to give 2-(2-formamidothiazol-4-yl)-2-(2-methylthiazol-4-ylmethoxyimino)acetic acid (synisomer, 1.17 g.).

후처리

  1. filtrationThe precipitates were collected by filtration
  2. washwashed with methanol

출처 및 근거

ORD 기록
ord-29e9f2b11d6047628a42d2b3a45d3983
출처 데이터셋
uspto-grants-1983_02
특허 번호
US04372952

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