HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 54271022, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | 1-Methylimidazole | HCID 1390 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 53636036 | HCID 53636036 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 54271022 | HCID 54271022 | 52.2% |
Reaction Steps
Ethyl 2-(2-aminothiazol-4-yl)-2-(4-chlorobenzyloxyimino)acetate (syn isomer, 21.15 g.), 1 N sodium hydroxide aqueous solution (94 ml.), 1-methylimidazole (1.02 g.), methanol (220 ml.) and tetrahydrofuran (150 ml.) were treated in a similar manner to that of Example P-(4) to give 2-(2-aminothiazol-4-yl)-2-(4-chlorobenzyloxyimino)acetic acid (syn isomer, 10.13 g.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04372952 |
| Source dataset | uspto-grants-1983_02 |
| ORD ID | ord-3765630c647f4d17964c18ccf0451991 |
| Source note | uspto-grants-1983_02 |