Dimethylformamide → HCID 131712962, compound

Participants

Reaction Steps

A mixture of 5.07 g (18.4 mmol) of the above quinolinecarboxylic acid, 5.97 g (36.8 mmol) carbonyldiimidazole, and 70 ml dimethylformamide is heated at 48° to 49° for 45 minutes and is stirred at room temperature overnight. The mixture is diluted with 150 ml of acetonitrile and filtered to yield 5.73 g of 6-[[(ethylamino)carbonyl]amino]-1,2-dihydro-2-oxo-3-quinolinecarboxylic acid imidazolide.

Provenance & Evidence