HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(((2-Aminoethyl)thio)methyl)-N,N-dimethyl-2-furanmethanamine → HCID 178494329, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(((2-Aminoethyl)thio)methyl)-N,N-dimethyl-2-furanmethanamine | HCID 162203 | — |
| Reactant | 3,4-Dimethoxy-1,2,5-thiadiazole 1,1-dioxide | HCID 12230538 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178494329 | HCID 178494329 | — |
Reaction Steps
A solution of 2-[(5-dimethylaminomethyl-2-furylmethylthio]ethylamine (2.14 g; 10.0 mmoles) in 25 ml of dry methanol was added dropwise over 35 minutes to a well stirred suspension of 3,4-dimethoxy-1,2,5-thiadiazole 1,1-dioxide (1.78 g; 10.0 mmoles) in 180 ml of dry methanol that had been cooled to 1° in an ice-water bath. After 15 minutes at 0°, a methanol solution of the title compound is produced. A TLC [silica/CH2Cl2 :CH3OH (9:1)] gave Rf=0.48.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04374248 |
| Source dataset | uspto-grants-1983_02 |
| ORD ID | ord-0b845c11d61c456e9fc3467dde9a674f |
| Source note | uspto-grants-1983_02 |