Ammonia → HCID 178512640, compound

HRID 1758639Notes

Reaction equation

HRID 1758639 reaction equation
CO[C:3]1[C:7](OC)=[N:6][S:5](=[O:10])[N:4]=1.[NH:11]([C:15]1[S:16][CH:17]=[C:18]([CH2:20][CH2:21][CH2:22][CH2:23][NH2:24])[N:19]=1)[C:12]([NH2:14])=[NH:13].[NH3:25]>>[NH2:25][C:3]1[C:7]([NH:24][CH2:23][CH2:22][CH2:21][CH2:20][C:18]2[N:19]=[C:15]([NH:11][C:12]([NH2:14])=[NH:13])[S:16][CH:17]=2)=[N:6][S:5](=[O:10])[N:4]=1

Participants

4

Reactant 3

HCID 222AmmoniaHCID 129139473,4-Dimethoxy-1,2,5-thiadiazole 1-oxideHCID 178512644HCID 178512644, compound

Product 1

HCID 178512640HCID 178512640, compound

Procedure

When a methanolic solution of 3,4-dimethoxy-1,2,5-thiadiazole 1-oxide is successively treated with 4-(2-guanidinothiazol-4-yl)butylamine [prepared according to the procedure described in U.S. Pat. No. 4,165,377] and excess anhydrous ammonia according to the general procedure described in Example 35, the title compound is thereby produced.

Workup

  1. customprepared

Sources & evidence

ORD record
ord-b2b4c936f6784029bb037eb186d33519
Source dataset
uspto-grants-1983_02
Patent number
US04374248

Reaction notes

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