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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1758695Generated: November 3, 2026

Bromine → 3-BROMO-4-(4-FLUOROPHENYL)-4-OXOBUTANOIC ACID

https://huagongshe.com/reaction/1758695

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromineHCID 24408—
Reactant3-(4-Fluorobenzoyl)propionic acidHCID 101359—
SolventAcetic AcidHCID 176—
Product3-BROMO-4-(4-FLUOROPHENYL)-4-OXOBUTANOIC ACIDHCID 3896139—

Reaction Steps

A mixture of 3-(4-fluorobenzoyl)propionic acid (0.01 mole) and bromine (0.012 mole) in acetic acid is stirred at room temperature for 16 hours. The solvent is removed to give 3-bromo-3-(4-fluorobenzoyl)propionic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04374249
Source datasetuspto-grants-1983_02
ORD IDord-2ff560a2c66e40ed954266db1761ee30
Source noteuspto-grants-1983_02