Hydrogen Bromide → HCID 54019721, compound

Participants

Reaction Steps

A mixture of 1.0 g. of [4R]-3-(2-acetylthio-3-benzoylpropionyl)-4-thiazolidinecarboxylic acid, 2,4,6-trimethylbenzyl ester, 10 ml. of acetic acid and 10 ml. of acetic acid saturated with hydrogen bromide gas is stirred at room temperature for 10 hours. The solvent is removed and the residue is chromatographed on a column of silica gel to give the product of the Example as a glass.

Provenance & Evidence