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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1758841Generated: October 25, 2026

L-Tryptophan, methyl ester → HCID 53931010, compound

https://huagongshe.com/reaction/1758841

Reaction equation

Participants

RoleNameHCIDCharge
ReactantL-Tryptophan, methyl esterHCID 77980—
ReactantSodium cyanoborohydrideHCID 5003444—
Reactant(S)-1-(2-Oxopropanoyl)pyrrolidine-2-carboxylic acidHCID 10130260—
ProductHCID 53931010HCID 53931010—

Reaction Steps

In a manner similar to Example 16 tryptophan methyl ester is condensed with pyruvoyl-L-proline in the presence of sodium cyanoborohydride to yield N-[1-methoxycarbonyl-2-(3-indolyl)-ethyl]-alanyl-L-proline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04374829
Source datasetuspto-grants-1983_02
ORD IDord-ba301a032f124fbd82178d023347e5f9
Source noteuspto-grants-1983_02