HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 6-Amino-1-ethyl-5-nitroso-1,3-dihydropyrimidine-2,4-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 6-Amino-1-ethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione | HCID 853899 | — |
| Reactant | Sodium Nitrite | HCID 23668193 | — |
| Solvent | Water | HCID 962 | — |
| Product | 6-Amino-1-ethyl-5-nitroso-1,3-dihydropyrimidine-2,4-dione | HCID 300509 | — |
Reaction Steps
To 100 g (0.65 mol) of 6-amino-1-ethyl-2,4-(1H,3H)-pyrimidinedione (II), dissolved in 1 liter hot water, was added 145 ml of 5 N HCl and 50 g of NaNO2 (0.72 mol) which was dissolved in water. After cooling the red crystals were filtered off and washed with water. Yield 97.7 g (83%) (III) NMR.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04338319 |
| Source dataset | uspto-grants-1982_07 |
| ORD ID | ord-86551b63bed64c08a05597d55afd581e |
| Source note | uspto-grants-1982_07 |