HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → 2-Furancarboxaldehyde, 5-(3,4-dimethoxyphenyl)-, O-[(methylamino)carbonyl]oxime
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Methyl Isocyanate | HCID 12228 | — |
| Reactant | N-{[5-(3,4-Dimethoxyphenyl)furan-2-yl]methylidene}hydroxylamine | HCID 71382179 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-Furancarboxaldehyde, 5-(3,4-dimethoxyphenyl)-, O-[(methylamino)carbonyl]oxime | HCID 54034316 | 51% |
Reaction Steps
5-(3,4-Dimethoxyphenyl)furylformaldoxime (9.5 g, 0.038 mole) and DMF (500 ml) was treated with methyl isocyanate (16 ml, 0.27 mole). The solution was stirred at room temperature for 4 hours and at steam bath temperature for 1 hour. The reaction solution was poured into 3 liters of water. The tan precipitate was collected to give 6 g (51%) of product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04339386 |
| Source dataset | uspto-grants-1982_07 |
| ORD ID | ord-82648de394dd45e3bbedeb24bc1918e0 |
| Source note | uspto-grants-1982_07 |