1,3-Propanediamine → HCID 66880063, compound

HRID 1759166Notes

Reaction equation

HRID 1759166 reaction equation
[C:1]([PH:4](=[O:6])[O-:5])(=O)[CH3:2].[Na+:7].[NH2:8][CH2:9][CH2:10][CH2:11][NH2:12].C1(C)C=CC=CC=1>C(O)C>[CH3:2][C:1]1([P:4]([O-:6])[O-:5])[NH:12][CH2:11][CH2:10][CH2:9][NH:8]1.[Na+:7].[Na+:7]

Participants

5

Reactant 3

HCID 4281,3-PropanediamineHCID 1140TolueneHCID 178476842HCID 178476842, compound

Product 1

HCID 66880063HCID 66880063, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent3×

Procedure

Sodium acetylphosphinate (2.6 g, 0.02 mol) and 1,3-diaminopropane (1.7 ml, 1.5 g, 0.02 mol) were stirred together in ethanol (60 ml) for 21/2 days, giving a cloudy pale yellow solution. This was evaporated inder reduced pressure, giving a sticky hydroscopic yellow solid, which contains ethanol by nmr. The solid was dissolved in ethanol, toluene added and re-evaporated to dryness, giving a yellow foam, mp 144°-6°, decomp (3.2 g, 86%). NMR was consistent with the desired structure.

Workup

  1. customgiving a cloudy pale yellow solution
  2. customThis was evaporated inder reduced pressure
  3. customgiving a sticky hydroscopic yellow solid, which
  4. customre-evaporated to dryness
  5. customgiving a yellow foam, mp 144°-6°, decomp (3.2 g, 86%)

Sources & evidence

ORD record
ord-ff1ac2835e89413a872d324b190c5c03
Source dataset
uspto-grants-1982_07
Patent number
US04339443

Reaction notes

Loading…