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Morpholine → 3-Amino-2-bromophenylmethyl acetate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Morpholine | HCID 8083 | — |
| 反応物 | 2-Bromo-3-nitrobenzyl acetate | HCID 12853052 | — |
| 触媒 | Platinum oxide (PtO) | HCID 82844 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 3-Amino-2-bromophenylmethyl acetate | HCID 20270620 | 115.5% |
反応手順
A mixture of 5.7 grams (0.022 mole) of 2-bromo-3-nitrophenylmethyl acetate, 0.1 gram of platinum oxide and 2.0 ml of morpholine in 200 ml of methanol was hydrogenated using a Parr hydrogenator. The hydrogenation required 2.25 hours. The reaction mixture was filtered and the filtrate concentrated under reduced pressure to give 6.2 grams of 3-amino-2-bromophenylmethyl acetate.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04339457 |
| 出典データセット | uspto-grants-1982_07 |
| ORD ID | ord-f8cb00fc3ac04033af8ede1044e52bc9 |
| 出典メモ | uspto-grants-1982_07 |