Sulfuric Acid → HCID 13034464, compound

HRID 1759242Notes

Reaction equation

HRID 1759242 reaction equation
C([CH:5]1[CH:14]2[N:9]([CH2:10][CH:11]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)[CH2:12][CH2:13]2)[CH2:8][CH2:7][C:6]1=[O:21])(OC)=O.OS(O)(=O)=O.C([O-])([O-])=O.[Na+].[Na+]>>[C:15]1([CH:11]2[CH2:12][CH2:13][CH:14]3[N:9]([CH2:8][CH2:7][C:6](=[O:21])[CH2:5]3)[CH2:10]2)[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1

Participants

4

Reactant 3

HCID 1118Sulfuric AcidHCID 10340Sodium CarbonateHCID 13034463HCID 13034463, compound

Product 1

HCID 13034464HCID 13034464, compoundYield 96.5%

Procedure

The ketoester (II) (6.82 g.) was dissolved in 50 ml. 1.8 M H2SO4 and the mixture refluxed overnight. The solution was cooled and made alkaline with Na2CO3. The organic material was extracted with CHCl3, dried and solvent removed. Yield, 5.6 g. Some ester was still present so the mixture was recycled. The reaction was worked up as above. Yield, 5.25 g. (96.5% yield).

Workup

  1. temperatureThe solution was cooled
  2. extractionThe organic material was extracted with CHCl3
  3. customdried
  4. customsolvent removed
  5. customYield
  6. customYield

Sources & evidence

ORD record
ord-5579f8c5ea5a40c980453c7acc4d1eca
Source dataset
uspto-grants-1982_07
Patent number
US04339582

Reaction notes

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