4-Methylanisole → 4-Methoxybenzaldehyde

Participants

Reaction Steps

A 1.22 g quantity of p-methyl anisole and 23.0 g of ammonium cerium(IV) nitrate are placed into a reactor, and 100 ml of methanol is further placed into the reactor. The mixture is stirred at room temperature for about 30 minutes. After the completion of the reaction, the methanol is distilled off from the reaction mixture. The residue is diluted with water and then subjected to extraction with benzene three times. The extract is washed with an aqueous solution of sodium chloride, dried over anhydrous sodium sulfate and distilled to remove the solvent. The residue is distilled in a vacuum, giving 1.308 g of anisaldehyde (b.p. 90°-92° C./2 mm Hg). Yield: 96.2%.

Provenance & Evidence