HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-nitroaniline → 1-Chloro-2-isothiocyanato-4-nitrobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-nitroaniline | HCID 22691 | — |
| Reactant | Thioformaldehyde | HCID 79115 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 1-Chloro-2-isothiocyanato-4-nitrobenzene | HCID 92681 | — |
Reaction Steps
A mixture of 50 parts of 2-chloro-5-nitrobenzenamine, 33.4 parts of methanethial and 450 parts of 1,4-dioxane is stirred and refluxed for 4 hours. The reaction mixture is evaporated, yielding 62.2 parts of 1-chloro-2-isothiocyanato-4-nitrobenzene as a residue.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04340738 |
| Source dataset | uspto-grants-1982_07 |
| ORD ID | ord-5f4745cba6b3444c926ac0092442e845 |
| Source note | uspto-grants-1982_07 |