(2-Thienylmethyl)amine → HCID 12810653, compound

HRID 1759542Notes

Reaction equation

HRID 1759542 reaction equation
[C:1]1([O:7][S:8]([C:11]2[CH:16]=[C:15]([S:17](=[O:20])(=[O:19])[NH2:18])[C:14]([N:21]([CH3:28])[C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)=[CH:13][C:12]=2Cl)(=[O:10])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[S:30]1[CH:34]=[CH:33][CH:32]=[C:31]1[CH2:35][NH2:36]>>[C:1]1([O:7][S:8]([C:11]2[CH:16]=[C:15]([S:17](=[O:20])(=[O:19])[NH2:18])[C:14]([N:21]([CH3:28])[C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)=[CH:13][C:12]=2[NH:36][CH2:35][C:31]2[S:30][CH:34]=[CH:33][CH:32]=2)(=[O:10])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 34005(2-Thienylmethyl)amineHCID 12810651HCID 12810651, compound

Product 1

HCID 12810653HCID 12810653, compoundYield 94%

Procedure

182 g of 2-chloro-4-(N-methylanilino)-5-sulfamoylbenzene sulfonic acid phenyl ester (0.4 mol) are reacted with 0.5 liter of 2-thienylmethyl amine according to Example 1. Working up in the manner described in Example 1 gives 200 g of 2-(thienylmethylamino)-4-(N-methylanilino)-5-sulfamoylbenzene sulfonic acid phenyl ester in chromatographically pure form. Yield: 94% of the theory. The product sinters at a temperature above 90° C.

Sources & evidence

ORD record
ord-1185fbf7dc8a40ac803431e50515b5e3
Source dataset
uspto-grants-1982_07
Patent number
US04341773

Reaction notes

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