HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → HCID 178488101, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 178488100 | HCID 178488100 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 178488101 | HCID 178488101 | 49% |
Reaction Steps
2 ml of trifluoroacetic acid is added to 25 mg of ester 4-5a in 5 ml of dichloromethane, followed by agitating for 3 hours at ambient temperature then adding toluene. After evaporating under reduced pressure, taking up in dichloromethane and crystallizing by adding an Et2O/pentane mixture, 11 mg of 4-6a is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06838453B2 |
| Source dataset | uspto-grants-2005_01 |
| ORD ID | ord-479ab0bbb5df4cfdbe66726ba8ea92de |
| Source note | uspto-grants-2005_01 |