HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4,5,6-Tetrahydropyrimidin-2-amine → HCID 86594985, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4,5,6-Tetrahydropyrimidin-2-amine | HCID 3287412 | — |
| Reactant | HCID 86594984 | HCID 86594984 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 86594985 | HCID 86594985 | 34.5% |
Reaction Steps
66 mg of 2-amino-1,4,5,6-tetrahydropyrimidine is added to a solution of 70 mg of 11-2 in 2 ml of THF, and agitation is carried out at ambient temperature for 3 hours. The reaction medium is then chromatographed eluting with a CH2Cl2/AcOEt mixture 80/20 then with MeOH/CH2Cl2 10/90. 27 mg of expected product 11-3 is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06838453B2 |
| Source dataset | uspto-grants-2005_01 |
| ORD ID | ord-31a75fdd97d44b06a0c9f32d01d5cbb9 |
| Source note | uspto-grants-2005_01 |