Sulfuryl chloride → HCID 135552969, compound

HRID 1759739Notes

Reaction equation

[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[C:10]1[NH:15][C:14](=[O:16])[C:13]2=[C:17]([CH2:20]CCCCCC)[N:18]=[CH:19][N:12]2[N:11]=1)[CH3:2].[S:27]([Cl:31])(Cl)(=[O:29])=[O:28]>>[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][C:7]([S:27]([Cl:31])(=[O:29])=[O:28])=[CH:6][C:5]=1[C:10]1[NH:15][C:14](=[O:16])[C:13]2=[C:17]([CH3:20])[N:18]=[C:19]([CH2:10][CH2:5][CH2:4][CH2:9][CH2:8][CH2:7][CH3:6])[N:12]2[N:11]=1)[CH3:2]

Participants

Reactant 2

HCID 24648Sulfuryl chloride

HCID 136378198HCID 136378198, compound

Product 1

HCID 135552969HCID 135552969, compound

Procedure

The preparation is carried out analogously to the procedure of Example 27A using 0.3 g (0.81 mmol) of 2-(2-ethoxyphenyl)-5-methyl-7-heptyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one (Example 22A). This gives 0.3 g (78.9%) of sulphonyl chloride as a white foam which is directly reacted further.

Sources & evidence

ORD record: ord-5c0e0833327f4544a403822814cbfba9
Source dataset: uspto-grants-2005_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06838459B1

Reaction notes

Loading…