反应详情

To a solution of 2,3-dimethoxyphenylacetic acid (2.52 g, 12.8 mmol) in EtOH (abs.; 20 mL) was added H2SO4 (30 μL), and the solution was refluxed for 20 hours. The resultant solution was concentrated, dissolved in ether, and the ether solution was washed with NaHCO3/aq (2×30 mL) and brine, dried (MgSO4) and concentrated to yield the sub-title compound.

1. temperaturethe solution was refluxed for 20 hours
2. concentrationThe resultant solution was concentrated
3. dissolutiondissolved in ether
4. washthe ether solution was washed with NaHCO3/aq (2×30 mL) and brine
5. dry with materialdried (MgSO4)
6. concentrationconcentrated