m-Anisoyl chloride → HCID 178490486, compound

HRID 1760175Notes

Reaction equation

HRID 1760175 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:11]2[NH:15][N:14]=[C:13]([CH3:16])[C:12]=2[NH2:17])[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].[CH3:18][O:19][C:20]1[CH:21]=[C:22]([CH:26]=[CH:27][CH:28]=1)[C:23](Cl)=[O:24]>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:11]2[NH:15][N:14]=[C:13]([CH3:16])[C:12]=2[NH:17][C:23](=[O:24])[C:22]2[CH:26]=[CH:27][CH:28]=[C:20]([O:19][CH3:18])[CH:21]=2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10]

Participants

3

Reactant 2

HCID 74374m-Anisoyl chlorideHCID 178489090HCID 178489090, compound

Product 1

HCID 178490486HCID 178490486, compound

Procedure

The preparation took place in analogy with Example 15a), starting with 300 mg of 5-(3,4-dimethoxyphenyl)-3-methyl-1H-pyrazol-4-ylamine (44) and 242 mg of 3-methoxybenzoyl chloride. The following was obtained: 53 C20H21N3O4 (367.41) MS (ESI) 368 (M+H)

Workup

  1. customThe following was obtained

Sources & evidence

ORD record
ord-a76b4830f133432d8f3a406e48c2e6f9
Source dataset
uspto-grants-2005_01
Patent number
US06841556B2

Reaction notes

Loading…