HCID 12136959, compound → HCID 178516226, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 1.80 g of 2-(3-fluorophenyl)-3-(6-methoxy-3-pyridyl) -3H-imidazo[4,5-b]pyridine and 20 mL of 47% hydrobromic acid was stirred at 100° C. for 3 hours and 35 minutes. The reaction mixtures was evaporated, to give a brown oil. This oil was subjected 3 times to azeotropic distillation with toluene, and the resulting brown oil was subjected to crystallization from methanol, to give 1.07 g of the title compound as greenish brown crystals (63% y.).

Provenance & Evidence