HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nitric Acid → HCID 22597841, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nitric Acid | HCID 944 | — |
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 5-nitro-1,2,3,4-tetrahydroisoquinoline | HCID 11379906 | — |
| Solvent | Sulfuric Acid | HCID 1118 | — |
| Product | HCID 22597841 | HCID 22597841 | — |
Reaction Steps
5-Nitro-1,2,3,4-tetrahydroisoquinoline (1.0 g, 5.6 mmol) in conc. sulfuric acid (3 ml) was treated with conc. nitric acid (1 ml) and the mixture stirred at room temperature for 1 h. The mixture was cooled, basified with 40% aqueous NaOH and work-up with dichloromethane gave the title compound (1.14 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06841560B2 |
| Source dataset | uspto-grants-2005_01 |
| ORD ID | ord-0feba509f9174a19808a4407d52322ff |
| Source note | uspto-grants-2005_01 |