Hydrogen iodide → HCID 22596106, compound

Participants

Reaction Steps

1′-[4-[1-(4-fluorophenyl)-1H-indole-3-yl]-1-butyl]-spiro[isobenzofuran-1(3H),4′-piperidine] (1.0 g, oil) and 2-propanole (15 ml) was stirred and heated until the oil was dissolved. Aqueous hydroiodic acid (1 ml, 57% HI) was added dropwise and crystals of the title compound was formed. More 2-propanole (10 ml) and hydrobromic acid (4 ml, 57% HI) was added to the suspension. The suspension was cooled on ice and the precipitate was filtered off and dried.

Provenance & Evidence