Oxalic Acid → HCID 68889020, compound

Participants

Reaction Steps

(R)-4,6,10-Trimethyl-3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one (200 mg, 0.88 mmol) was reacted with lithium aluminium hydride in accordance with the general method of example 1a). The crude material obtained was dissolved in ether (10 mL) and treated with oxalic acid solution (20% in ethanol, 7 mL). The precipitate was collected by filtration and dried to afford the title compound (196 mg, 74%). White solid. Anal. calc. for C16H20N2O4: C, 63.14; H, 6.62; N, 9.20; found: C, 62.86; H, 6.87; N, 8.92%.

Provenance & Evidence