HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminobenzyl alcohol → HCID 22594274, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminobenzyl alcohol | HCID 21439 | — |
| Reactant | Dimethyl 3-oxoglutarate | HCID 74591 | — |
| Reactant | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Solvent | 1,1-Dichloroethane | HCID 6365 | — |
| Product | HCID 22594274 | HCID 22594274 | — |
Reaction Steps
There are added in succession, to a solution of dimethyl 3-oxopentanedioate (5 g; 28.71 mmol; 4.2 ml) in dichloroethane (125 ml) at 0° C., (2-aminophenyl)methanol (2.95 g; 23.93 mol), and then NaBH(OAc)3 (6 g; 28.71 mol) in small portions.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06846833B2 |
| Source dataset | uspto-grants-2005_01 |
| ORD ID | ord-c2b821fcd84440a28155fc4d5f66234b |
| Source note | uspto-grants-2005_01 |